CIRBP
Sign in to saveAlso known as CIRP, cold inducible RNA binding protein
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia. It is thought to be involved in DNA repair.
Gene data
CIRBP- Name
- cold inducible RNA binding protein
- Type
- protein-coding
- Position
- 1,259,384–1,274,880 (+)
- Aliases
- CIRP
- Ensembl
- ENSG00000099622
- RefSeq RNA
- NM_001280.3, NM_001300815.2, NM_001300829.2, NM_001437523.1, NM_001437524.1
- RefSeq protein
- NP_001271.1, NP_001287744.1, NP_001287758.1, NP_001424452.1, NP_001424453.1
Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
cold inducible RNA binding protein
- Symbol
- CIRBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:1,259,384-1,274,880
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia. It is thought to be involved in DNA repair.
== References ==
Excerpted from Wikipedia’s “CIRBP” article, available under the CC BY-SA 4.0 licence.