CLDN2

Also known as claudin 2, OAZON

Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.

Gene data

CLDN2

Name: claudin 2
Type: protein-coding
Chromosome: X
Aliases: OAZON, claudin-2

This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010].

via MyGene.info

Gene · Ensembl

claudin 2

Symbol: CLDN2
Biotype: Protein coding
Organism: Homo sapiens
Location: Chr X:106,892,766-106,930,862
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 9621
exact match: identifiers.org/ncbigene/9075
genomic start: 106143394
genomic end: 106174091
cytogenetic location: Xq22.3

Sources (3)

via Wikidata · CC0

~1 min read

Article

4 sections

Contents

Function
References
External links
Further reading

Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.

Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[supplied by OMIM]