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Clean-in-place

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thumb|A clean-in-place unit on display at the World of Coca-Cola in [[Atlanta]] Clean-in-place (CIP) is an automated method of cleaning the interior surfaces of pipes, vessels, equipment, filters and associated fittings, without major disassembly. CIP is commonly used for equipment such as piping, tanks, and fillers. CIP employs turbulent flow through piping, and/or spray balls for tanks or vessels. In some cases, CIP can also be accomplished with fill, soak and agitate.

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technique
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Encyclopedic overview

6 sections
Contents
  • Factors affecting the effectiveness of the cleaning agents
  • Groundwater sources
  • Biomanufacturing Equipment
  • Validation and Verification of CIP
  • See also
  • References

thumb|A clean-in-place unit on display at the World of Coca-Cola in [[Atlanta]] Clean-in-place (CIP) is an automated method of cleaning the interior surfaces of pipes, vessels, equipment, filters and associated fittings, without major disassembly. CIP is commonly used for equipment such as piping, tanks, and fillers. CIP employs turbulent flow through piping, and/or spray balls for tanks or vessels. In some cases, CIP can also be accomplished with fill, soak and agitate.

Up to the 1950s, closed systems were disassembled and cleaned manually. The advent of CIP was a boon to industries that needed frequent internal cleaning of their processes. Industries that rely heavily on CIP are those requiring high levels of hygiene, and include: dairy, beverage, brewing, processed foods, pharmaceutical, and cosmetics. A well designed CIP system is needed to accomplish required results from CIP.

Excerpted from Wikipedia’s “Clean-in-place” article, available under the CC BY-SA 4.0 licence.

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