CLEC4A
Sign in to saveAlso known as CLECSF6, DCIR, DDB27, LLIR, CD367, HDCGC13P, C-type lectin domain family 4 member A, hDCIR
C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.
In the Vinony graph
Within Vinony's link graph, CLEC4A is referenced by 5 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It sits within the topics C-type lectins and Genes on human chromosome 12.
Its subject is documented across 6 Wikipedia language editions.
Gene data
CLEC4A- Name
- C-type lectin domain family 4 member A
- Type
- protein-coding
- Position
- 8,123,617–8,138,607 (+)
- Aliases
- CD367, CLECSF6, DCIR, DDB27, HDCGC13P, LLIR, hDCIR
- Ensembl
- ENSG00000111729
- RefSeq RNA
- NM_016184.4, NM_194447.3, NM_194448.3, NM_194450.3, XM_011520684.3
- RefSeq protein
- NP_057268.1, NP_919429.2, NP_919430.1, NP_919432.1, XP_011518986.1
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
C-type lectin domain family 4 member A
- Symbol
- CLEC4A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:8,123,617-8,138,607
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 49291
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/50856
- genomic end
- 8291203
- genomic start
- 8123617
- chromosome
- human chromosome 12
- cytogenetic location
- 12p13.31
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
C-type lectin domain family 4 member A is a protein that in humans is encoded by the CLEC4A gene.
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response.
Excerpted from Wikipedia’s “CLEC4A” article, available under the CC BY-SA 4.0 licence.