CLK1
Sign in to saveAlso known as CLK, CLK/STY, STY, CDC like kinase 1
Dual specificity protein kinase CLK1 is an enzyme that in humans is encoded by the CLK1 gene.
Gene data
CLK1- Name
- CDC like kinase 1
- Type
- protein-coding
- Aliases
- CLK, CLK/STY, STY
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009].
via MyGene.info
Gene · Ensembl
CDC like kinase 1
- Symbol
- CLK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:200,853,009-200,864,728
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CLK1 PDB 1z57.png
Show 8 more facts
- HomoloGene ID
- 101535
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1195
- genomic end
- 200864691
- genomic start
- 201717732
- chromosome
- human chromosome 2
- cytogenetic location
- 2q33.1
- expressed in
- gastric mucosa
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Dual specificity protein kinase CLK1 is an enzyme that in humans is encoded by the CLK1 gene.
== Function ==
Excerpted from Wikipedia’s “CLK1” article, available under the CC BY-SA 4.0 licence.