CNTNAP4
Sign in to saveAlso known as CASPR4, contactin associated protein like 4, contactin associated protein family member 4
Contactin-associated protein-like 4 is a protein that in humans is encoded by the CNTNAP4 gene.
Gene data
CNTNAP4- Name
- contactin associated protein family member 4
- Type
- protein-coding
- Position
- 76,277,272–76,560,757 (+)
- Aliases
- CASPR4
- Ensembl
- ENSG00000152910
- RefSeq RNA
- NM_001322178.2, NM_001322179.2, NM_001322180.2, NM_001322181.2, NM_001322187.2
- RefSeq protein
- NP_001309107.1, NP_001309108.1, NP_001309109.1, NP_001309110.1, NP_001309116.1
This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
contactin associated protein family member 4
- Symbol
- CNTNAP4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:76,277,272-76,560,757
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 24912
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/85445
- genomic end
- 76560757
- genomic start
- 76311176
- chromosome
- human chromosome 16
- cytogenetic location
- 16q23.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Contactin-associated protein-like 4 is a protein that in humans is encoded by the CNTNAP4 gene.
This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. Alternative splicing results in two transcript variants encoding different isoforms.
Excerpted from Wikipedia’s “CNTNAP4” article, available under the CC BY-SA 4.0 licence.