coloboma
Sign in to saveAlso known as coloboma of eye, congenital ocular coloboma, Coloboma of the Eye, ocular coloboma, coloboma of macula
A coloboma (from the Greek , meaning "defect") is a hole in one of the structures of the eye, such as the iris, retina, choroid, or optic disc. The hole is present from birth and can be caused when a gap called the choroid fissure, which is present during early stages of prenatal development, fails to close up completely before a child is born. Ocular coloboma is relatively uncommon, affecting less than one in every 10,000 births.
Key facts
- Medical condition (new).name
- Coloboma
- Medical condition (new).field
- Ophthalmology
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- Coloboma of the iris.JPG
- Medical condition (new).caption
- Coloboma in a 16-year-old female
via Wikipedia infobox
Research
6,102 papers- Genetics of syndromic ocular coloboma: CHARGE and COACH syndromes.Experimental eye research · 2020
- The deceptive coloboma.Indian journal of ophthalmology · 2023
- Uveal coloboma: clinical and basic science update.Current opinion in ophthalmology · 2006
- Choroidal coloboma.Ophthalmology · 2007
- Classification of microphthalmos and coloboma.Journal of medical genetics · 1993
via PubMed
~5 min read
Encyclopedic overview
9 sectionsContents
- Signs and symptoms
- Related conditions
- Cause
- Diagnosis
- Treatment
- Epidemiology
- Society and culture
- References
- External links
A coloboma (from the Greek , meaning "defect") is a hole in one of the structures of the eye, such as the iris, retina, choroid, or optic disc. The hole is present from birth and can be caused when a gap called the choroid fissure, which is present during early stages of prenatal development, fails to close up completely before a child is born. Ocular coloboma is relatively uncommon, affecting less than one in every 10,000 births.
The classical description in medical literature is of a keyhole-shaped defect. A coloboma can occur in one eye (unilateral) or both eyes (bilateral). Most cases of coloboma affect only the iris. The level of vision impairment of those with a coloboma can range from having no vision problems to being able to see only light or dark, depending on the position and extent of the coloboma (or colobomata if more than one is present).
Excerpted from Wikipedia’s “coloboma” article, available under the CC BY-SA 4.0 licence.