COTL1
Sign in to saveAlso known as CLP, coactosin like F-actin binding protein 1
Coactosin-like protein (COTL1 or CLP) is a protein that in humans is encoded by the COTL1 gene.
Gene data
COTL1- Name
- coactosin like F-actin binding protein 1
- Type
- protein-coding
- Aliases
- CLP
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein COTL1 PDB 1t2l.png
Show 5 more facts
- HomoloGene ID
- 10898
- exact match
- identifiers.org/ncbigene/23406
- genomic start
- 84565596
- genomic end
- 84618078
- cytogenetic location
- 16q24.1
Sources (3)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Coactosin-like protein (COTL1 or CLP) is a protein that in humans is encoded by the COTL1 gene.
== Function ==