CPA4

Also known as CPA3, carboxypeptidase A4

protein-coding gene in the species Homo sapiens

Gene data

CPA4

Name: carboxypeptidase A4
Type: protein-coding
Position: 130,293,134–130,324,180 (+)
Aliases: CPA3
Ensembl: ENSG00000128510
RefSeq RNA: NM_001163446.2, NM_016352.4, XM_047420438.1, XM_054358328.1
RefSeq protein: NP_001156918.1, NP_057436.2, XP_047276394.1, XP_054214303.1

This gene is a member of the carboxypeptidase A/B subfamily, and it is located in a cluster with three other family members on chromosome 7. Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. This gene could be involved in the histone hyperacetylation pathway. It is imprinted and may be a strong candidate gene for prostate cancer aggressiveness. [provided by RefSeq, Jul 2008].