CRHBP
Sign in to saveAlso known as CRF-BP, CRFBP, corticotropin releasing hormone binding protein
Corticotropin-releasing factor-binding protein is a protein that in humans is encoded by the CRHBP gene. It belongs to corticotropin-releasing hormone binding protein family.
In the Vinony graph
Within Vinony's link graph, CRHBP is referenced by 5 other articles, and connects out to Q180686, human chromosome 5 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 5.
Its subject is documented across 7 Wikipedia language editions.
Gene data
CRHBP- Name
- corticotropin releasing hormone binding protein
- Type
- protein-coding
- Position
- 76,952,857–76,981,315 (+)
- Aliases
- CRF-BP, CRFBP
- Ensembl
- ENSG00000145708
- RefSeq RNA
- NM_001882.4, XM_047416736.1, XR_008487082.1, XR_948235.4
- RefSeq protein
- NP_001873.2, XP_047272692.1
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
corticotropin releasing hormone binding protein
- Symbol
- CRHBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:76,952,857-76,981,315
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1418
- exact match
- identifiers.org/ncbigene/1393
- genomic end
- 76276983
- genomic start
- 76953045
- cytogenetic location
- 5q13.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Corticotropin-releasing factor-binding protein is a protein that in humans is encoded by the CRHBP gene. It belongs to corticotropin-releasing hormone binding protein family.
Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Excerpted from Wikipedia’s “CRHBP” article, available under the CC BY-SA 4.0 licence.