CRLF1
Sign in to saveAlso known as CISS, CISS1, CLF, CLF-1, NR6, zcytor5, cytokine receptor like factor 1
Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.
Gene data
CRLF1- Name
- cytokine receptor like factor 1
- Type
- protein-coding
- Position
- 18,572,220–18,607,741 (−)
- Aliases
- CISS, CISS1, CLF, CLF-1, NR6, zcytor5
- Ensembl
- ENSG00000006016
- RefSeq RNA
- NM_004750.5
- RefSeq protein
- NP_004741.1
This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cytokine receptor like factor 1
- Symbol
- CRLF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:18,572,220-18,607,741
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3489
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9244
- genomic end
- 18718551
- genomic start
- 18683030
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.11
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Cytokine receptor-like factor 1 is a protein that in humans is encoded by the CRLF1 gene.
== Function ==
Excerpted from Wikipedia’s “CRLF1” article, available under the CC BY-SA 4.0 licence.