Cryogenine
Sign in to saveCryogenine, also known as vertine or (10α)-4,5-dimethoxy-2-hydroxylythran-12-one, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and H. myrtifolia. The compound has no psychoactive properties in humans up to 310 mg, but has shown anti-inflammatory activity similar to aspirin.
Wikidata facts
- Mass
- 435.204573
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- chemical formula
- C₂₆H₂₉NO₅
- canonical SMILES
- COC1=C(C=C2C(=C1)C3CC(CC4N3CCCC4)OC(=O)C=CC5=CC2=C(C=C5)O)OC
- isomeric SMILES
- [H][C@]1([C@H]2N([C@@H]3C4=CC(=C(C=C4C5=C(C=CC(=C5)/C=C\C(=O)O[C@@H](C2)C3)O)OC)OC)CCC1)[H]
- found in taxon
- Heimia salicifolia
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Encyclopedic overview
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- References
Cryogenine, also known as vertine or (10α)-4,5-dimethoxy-2-hydroxylythran-12-one, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and H. myrtifolia. The compound has no psychoactive properties in humans up to 310 mg, but has shown anti-inflammatory activity similar to aspirin.
The freebase form melts at 250–251 °C and is soluble in moderately polar organic solvents such as chloroform, methylene chloride, benzene, and methanol, but is insoluble in water and petroleum ether.
Excerpted from Wikipedia’s “Cryogenine” article, available under the CC BY-SA 4.0 licence.