CST1
Sign in to saveAlso known as cystatin SN
Cystatin-SN is a protein that in humans is encoded by the CST1 gene.
Gene data
CST1- Name
- cystatin SN
- Type
- protein-coding
- Position
- 23,747,560–23,751,268 (−)
- Ensembl
- ENSG00000170373
- RefSeq RNA
- NM_001898.3
- RefSeq protein
- NP_001889.2
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
cystatin SN
- Symbol
- CST1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:23,747,560-23,751,268
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 88653
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1469
- genomic end
- 23731905
- genomic start
- 23747562
- chromosome
- human chromosome 20
- cytogenetic location
- 20p11.21
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cystatin-SN is a protein that in humans is encoded by the CST1 gene.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid.
Excerpted from Wikipedia’s “CST1” article, available under the CC BY-SA 4.0 licence.