CST5
Sign in to saveAlso known as cystatin D
Cystatin-D is a protein that in humans is encoded by the CST5 gene.
Gene data
CST5- Name
- cystatin D
- Type
- protein-coding
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
cystatin D
- Symbol
- CST5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:23,875,934-23,880,086
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CST5 PDB 1rn7.png
Show 8 more facts
- HomoloGene ID
- 55615
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1473
- genomic end
- 23879748
- genomic start
- 23875934
- chromosome
- human chromosome 20
- cytogenetic location
- 20p11.21
- expressed in
- muscle tissue
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cystatin-D is a protein that in humans is encoded by the CST5 gene.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.
Excerpted from Wikipedia’s “CST5” article, available under the CC BY-SA 4.0 licence.