CTCFL

Also known as BORIS, CT27, CTCF-T, HMGB1L1, dJ579F20.2, CCCTC-binding factor like

Transcriptional repressor CTCFL also known as BORIS (Brother of Regulator of Imprinted Sites) is a protein that in humans is encoded by the CTCFL gene.

Gene data

CTCFL

Name: CCCTC-binding factor like
Type: protein-coding
Aliases: BORIS, CT27, CTCF-T, HMGB1L1, dJ579F20.2

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].

via MyGene.info

Wikidata facts

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HomoloGene ID: 46476
exact match: identifiers.org/ncbigene/140690
cytogenetic location: 20q13.31

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Contents

Function
References
Further reading
External links

Transcriptional repressor CTCFL also known as BORIS (Brother of Regulator of Imprinted Sites) is a protein that in humans is encoded by the CTCFL gene.

== Function ==