CTNNBL1
Sign in to saveAlso known as C20orf33, NAP, P14L, PP8304, dJ633O20.1, catenin beta like 1, IMD99
Beta-catenin-like protein 1 is a protein that in humans is encoded by the CTNNBL1 gene.
Gene data
CTNNBL1- Name
- catenin beta like 1
- Type
- protein-coding
- Aliases
- C20orf33, IMD99, NAP, P14L, PP8304, dJ633O20.1
The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013].
via MyGene.info
Gene · Ensembl
catenin beta like 1
- Symbol
- CTNNBL1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:37,693,949-37,872,129
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Beta-catenin-like protein 1 is a protein that in humans is encoded by the CTNNBL1 gene.
The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity. It is a housekeeping gene.
Excerpted from Wikipedia’s “CTNNBL1” article, available under the CC BY-SA 4.0 licence.