CUL2
Sign in to saveAlso known as cullin 2
Cullin-2 is a protein that in humans is encoded by the CUL2 gene.
Gene data
CUL2- Name
- cullin 2
- Type
- protein-coding
- Position
- 35,008,465–35,127,006 (−)
- Ensembl
- ENSG00000108094
- RefSeq RNA
- NM_001198777.2, NM_001198778.2, NM_001198779.1, NM_001324375.2, NM_001324376.2
- RefSeq protein
- NP_001185706.1, NP_001185707.1, NP_001185708.1, NP_001311304.1, NP_001311305.1
Enables ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to act upstream of or within protein catabolic process. Located in nucleoplasm. Part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
G1/S transition of mitotic cell cycleG1/S transition of mitotic cell cyclenegative regulation of transcription by RNA polymerase IIubiquitin-dependent protein catabolic processprotein ubiquitinationprotein ubiquitinationprotein ubiquitinationSCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Molecular function
Cellular component
Pathways
HIF-1 signaling pathway - Homo sapiens (human)Ubiquitin mediated proteolysis - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Renal cell carcinoma - Homo sapiens (human)Cellular response to hypoxiaCellular response to hypoxiaOxygen-dependent proline hydroxylation of Hypoxia-inducible Factor AlphaOxygen-dependent proline hydroxylation of Hypoxia-inducible Factor AlphaDevelopmental BiologyAdaptive Immune System
via MyGene.info
Gene · Ensembl
cullin 2
- Symbol
- CUL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:35,008,465-35,127,006
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Cullin-2 is a protein that in humans is encoded by the CUL2 gene.
== Interactions ==
Excerpted from Wikipedia’s “CUL2” article, available under the CC BY-SA 4.0 licence.