DAZAP2

Name

DAZ associated protein 2

Type

protein-coding

Position

51,238,724–51,272,164 (+)

Aliases

PRTB

Ensembl

ENSG00000183283

RefSeq RNA

NM_001136264.2, NM_001136266.2, NM_001136267.2, NM_001136268.2, NM_001136269.2

RefSeq protein

NP_001129736.1, NP_001129738.1, NP_001129739.1, NP_001129740.1, NP_001129741.1

This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

via MyGene.info

Gene · Ensembl

DAZ associated protein 2

Symbol

DAZAP2

Biotype

Protein coding

Organism

Homo sapiens

Location

12:51,238,724-51,272,164

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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