DCLRE1B
Sign in to saveAlso known as APOLLO, SNM1B, SNMIB, DNA cross-link repair 1B
DNA cross-link repair 1B protein is a protein that in humans is encoded by the DCLRE1B gene.
Gene data
DCLRE1B- Name
- DNA cross-link repair 1B
- Type
- protein-coding
- Position
- 113,904,403–113,914,140 (+)
- Aliases
- APOLLO, DKCB8, SNM1B, SNMIB
- Ensembl
- ENSG00000118655
- RefSeq RNA
- NM_001319946.2, NM_001319947.2, NM_001363690.2, NM_001363691.2, NM_022836.4
- RefSeq protein
- NP_001306875.1, NP_001306876.1, NP_001350619.1, NP_001350620.1, NP_073747.1
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000 [PubMed 10848582]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DNA cross-link repair 1B
- Symbol
- DCLRE1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:113,904,403-113,914,140
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 32553
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/64858
- genomic end
- 114456708
- genomic start
- 113905213
- chromosome
- human chromosome 1
- cytogenetic location
- 1p13.2
- expressed in
- trabecular bone
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
DNA cross-link repair 1B protein is a protein that in humans is encoded by the DCLRE1B gene.
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000).[supplied by OMIM] ==Function==
Excerpted from Wikipedia’s “DCLRE1B” article, available under the CC BY-SA 4.0 licence.