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GeneQ5204554· pop 6· linked from 3 articles

Also known as dynactin subunit 5

Dynactin 5 (p25) is a protein that in humans is encoded by the DCTN5 gene.

Gene data

DCTN5
Name
dynactin subunit 5
Type
protein-coding
Position
23,641,380–23,677,472 (+)
RefSeq RNA
NM_001199011.2, NM_001199743.2, NM_032486.4, NR_037573.2, XR_001752006.3
RefSeq protein
NP_001185940.1, NP_001186672.1, NP_115875.1

This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

Gene Ontology

Molecular function

via MyGene.info

Gene · Ensembl

dynactin subunit 5

Symbol
DCTN5
Biotype
Protein coding
Organism
Homo sapiens
Location
16:23,641,380-23,677,472
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Dynactin 5 (p25) is a protein that in humans is encoded by the DCTN5 gene.

This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Excerpted from Wikipedia’s “DCTN5” article, available under the CC BY-SA 4.0 licence.

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