Structure via PubChem · Public domain (PubChem)
dimethyl sulfate
Sign in to saveAlso known as Sulfuric acid dimethyl ester, Dimethyl ester of sulfuric acid, Dimethylsulfate, Methyl sulfate, DMS, Dimethoxysulfone, Dimethyl monosulfate, Dimethyl sulphate
chemical compound
Chemical data
- Formula
- C2H6O4S
- Molecular weight
- 126.13 g/mol
- IUPAC name
- dimethyl sulfate
- SMILES
- COS(=O)(=O)OC
- InChIKey
- VAYGXNSJCAHWJZ-UHFFFAOYSA-N
- XLogP
- -0.3
- Polar surface area
- 61 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
1,425 papers- Dimethyl sulfate.IARC monographs on the evaluation of carcinogenic risks to humans · 1999
- Dimethyl sulfate.Report on carcinogens : carcinogen profiles · 2011
- Determination of Residual Dimethyl Sulfate in Cephalosporin Using HS-SPME/GC-MS.Journal of chromatographic science · 2024
- DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo.Nature methods · 2017
- Dimethyl sulfate.Report on carcinogens : carcinogen profiles · 2002
via PubMed
Wikidata facts
Show 13 more facts
- decomposition point
- 370
- flash point
- 182
- canonical SMILES
- COS(=O)(=O)OC
- Commons category
- Dimethyl sulfate
- NIOSH Pocket Guide ID
- 0229
- density
- 1.33
- immediately dangerous to life or health
- 36.12
- melting point
- -25
- solubility
- 3
- vapor pressure
- 0.1
- time-weighted average exposure limit
- 5
- chemical formula
- C₂H₆O₄S
- subject has role
- carcinogen
via Wikidata · CC0
~6 min read
Encyclopedic overview
Dimethyl sulfate (DMS) is a chemical compound with formula (CH3O)2SO2. As the diester of methanol and sulfuric acid, its formula is often written as (CH3)2SO4 or Me2SO4, where CH3 or Me is methyl. Me2SO4 is mainly used as a methylating agent in organic synthesis. Me2SO4 is a colourless oily liquid with a slight onion-like odour. Like all strong alkylating agents, Me2SO4 is highly toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, CF3SO3CH3, the methyl ester of trifluoromethanesulfonic acid.
History
Excerpted from Wikipedia’s “dimethyl sulfate” article, available under the CC BY-SA 4.0 licence.