DPP6

Name

dipeptidyl peptidase like 6

Type

protein-coding

Position

153,748,133–154,894,285 (+)

Aliases

DPL1, DPPX, MRD33, VF2

Ensembl

ENSG00000130226

RefSeq RNA

NM_001039350.3, NM_001290252.2, NM_001290253.2, NM_001364497.2, NM_001364498.2

RefSeq protein

NP_001034439.1, NP_001277181.1, NP_001277182.1, NP_001351426.1, NP_001351427.1

This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

via MyGene.info

Gene · Ensembl

dipeptidyl peptidase like 6

Symbol

DPP6

Biotype

Protein coding

Organism

Homo sapiens

Location

7:153,748,133-154,894,285

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein DPP6 PDB 1xfd.png

via Wikidata · CC0