DSN1
Sign in to saveAlso known as C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3, DSN1 homolog, MIS12 kinetochore complex component, DSN1 component of MIS12 kinetochore complex
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.
Gene data
DSN1- Name
- DSN1 component of MIS12 kinetochore complex
- Type
- protein-coding
- Position
- 36,751,791–36,774,298 (−)
- Aliases
- C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3
- Ensembl
- ENSG00000149636
- RefSeq RNA
- NM_001145315.2, NM_001145316.2, NM_001145317.2, NM_001145318.2, NM_024918.4
- RefSeq protein
- NP_001138787.1, NP_001138788.1, NP_001138789.1, NP_001138790.1, NP_079194.3
This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DSN1 component of MIS12 kinetochore complex
- Symbol
- DSN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:36,751,791-36,774,298
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.
==Function== DSN1 along with MIS12, DC8, PMF1, CBX5, ZWINT is a component of the kinetochore-associated multiprotein complex which is required for correct chromosome alignment during the metaphase of cell mitosis.
Excerpted from Wikipedia’s “DSN1” article, available under the CC BY-SA 4.0 licence.