E. Donnall Thomas
Sign in to saveAmerican hematologist (1920-2012)
AI overview
E. Donnall Thomas was an American hematologist who pioneered bone marrow transplantation, a medical technique that has saved countless lives by replacing diseased blood-forming cells with healthy ones. His groundbreaking work in the field earned him the Nobel Prize in Physiology or Medicine, making him one of the most influential medical researchers of the 20th century.
AI-generated from the Wikipedia summary — may contain errors.
Person · Open Library
- Born
- 1920-03-15
- Died
- 2012-10-20
- Works
- 18
Top works
- How Sportsmen Saved the World
- To all things a season
- Fool hen blues
- Fly fishing
- Classic papers in hematological oncology
via Open Library + Wikidata
Recent publications · Crossref
5 total works indexed
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
· 2001 · cited 160,293x
Article
Edward Donnall "Don" Thomas (March 15, 1920 – October 20, 2012) was an American physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia.
Thomas was a lead investigator in a failed series of experimental treatments for leukemia and for Graft-versus-host disease at Seattle's Fred Hutchinson Cancer Research Center from 1981 to 1993. Participants were not informed that Thomas and other researchers had a potential financial conflict of interest in the trials, and were never properly informed of the risks. The study continued despite objections from members of the Center’s Internal Review Board. 84 of the 85 participants in the study died.
Gallery (2)
Connections
Categories
1920 births2012 deathsAmerican hematologistsAmerican Nobel laureatesColumbia University peopleHarvard Medical School alumniMembers of the United States National Academy of SciencesNational Medal of Science laureatesNobel laureates in Physiology or MedicinePhysicians of Brigham and Women's HospitalPresidents of the American Society of Hematology