EIF4ENIF1
Sign in to saveAlso known as 4E-T, Clast4, eukaryotic translation initiation factor 4E nuclear import factor 1
Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.
Gene data
EIF4ENIF1- Name
- eukaryotic translation initiation factor 4E nuclear import factor 1
- Type
- protein-coding
- Position
- 31,436,977–31,497,047 (−)
- Aliases
- 4E-T, Clast4
- Ensembl
- ENSG00000184708
- RefSeq RNA
- NM_001164501.2, NM_001164502.2, NM_019843.4, XM_005261686.4, XM_005261687.4
- RefSeq protein
- NP_001157973.1, NP_001157974.1, NP_062817.2, XP_005261743.1, XP_005261744.1
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 4E nuclear import factor 1
- Symbol
- EIF4ENIF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:31,436,977-31,497,047
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/56478
- HomoloGene ID
- 10522
- cytogenetic location
- 22q12.2
- genomic end
- 31892094
- genomic start
- 31832963
- chromosome
- human chromosome 22
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals.
Excerpted from Wikipedia’s “EIF4ENIF1” article, available under the CC BY-SA 4.0 licence.