EIF4ENIF1
Sign in to saveAlso known as 4E-T, Clast4, eukaryotic translation initiation factor 4E nuclear import factor 1
Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.
In the Vinony graph
Within Vinony's link graph, EIF4ENIF1 is referenced by 3 other articles, and connects out to PubMed, human chromosome 22 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 22.
Its subject is documented across 5 Wikipedia language editions.
Gene data
EIF4ENIF1- Name
- eukaryotic translation initiation factor 4E nuclear import factor 1
- Type
- protein-coding
- Position
- 31,436,977–31,497,047 (−)
- Aliases
- 4E-T, Clast4
- Ensembl
- ENSG00000184708
- RefSeq RNA
- NM_001164501.2, NM_001164502.2, NM_019843.4, XM_005261686.4, XM_005261687.4
- RefSeq protein
- NP_001157973.1, NP_001157974.1, NP_062817.2, XP_005261743.1, XP_005261744.1
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 4E nuclear import factor 1
- Symbol
- EIF4ENIF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:31,436,977-31,497,047
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/56478
- HomoloGene ID
- 10522
- cytogenetic location
- 22q12.2
- genomic end
- 31892094
- genomic start
- 31832963
- chromosome
- human chromosome 22
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Eukaryotic translation initiation factor 4E transporter is a protein that in humans is encoded by the EIF4ENIF1 gene.
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic;its own nuclear import is regulated by a nuclear localization signal and nuclear export signals.
Excerpted from Wikipedia’s “EIF4ENIF1” article, available under the CC BY-SA 4.0 licence.