Protein · UniProt
Elastin
- Gene
- ELN
- Organism
- Homo sapiens (Human)
- Length
- 786 aa
- Molecular mass
- 68,398 Da
- Evidence
- 1: Evidence at protein level
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity)
Swiss-Prot (reviewed) · via UniProt
Research
17,659 papers- Elastin.Advances in protein chemistry · 2005
- Elastin Biomaterials in Dermal Repair.Trends in biotechnology · 2020
- Elastin in the Tumor Microenvironment.Advances in experimental medicine and biology · 2020
- Elastin in healthy and diseased lung.Current opinion in biotechnology · 2022
- Fabricated Elastin.Advanced healthcare materials · 2015
via PubMed
Clinical Trials
20 registered- NACOMPLETEDEffects of Emotion on Episodic Memory in Typically Developing Children and Children With Williams-Beuren SyndromeHôpital le Vinatier · NCT03688516
- NACOMPLETEDThe Effects of Microdermabrasion on Skin RemodelingUniversity of Michigan · NCT00111254
- PHASE1/PHASE2ACTIVE_NOT_RECRUITINGA Study Assessing KB304 for the Treatment of Wrinkles in WomenKrystal Biotech, Inc. · NCT06724900
- UNKNOWNThe Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin DegradationCanisius-Wilhelmina Hospital · NCT03285100
- RECRUITINGCharacterization and Natural History of Williams Syndrome and Other Chromosome 7q11.23 VariantsUniversity of Pennsylvania · NCT06930417
- NACOMPLETEDEfficacy of Collagen-elastin Dermal Substitute in the Treatment of Loss of Cutaneous Substances With Skin GraftsUniversity Hospital, Rouen · NCT02090361
Article · Español
La elastina es una proteína del tejido conjuntivo con funciones estructurales que, a diferencia del colágeno que proporciona principalmente resistencia, confiere elasticidad a los tejidos. Se trata de un polímero con un peso molecular de 70 kDa con gran capacidad de expansión que recuerda ligeramente a una goma elástica. La elastina se encuentra presente en todos los vertebrados. La elastina es importante también en la capacidad de los cuerpos de los vertebrados para soportar esfuerzos, y aparece en mayores concentraciones donde se requiere almacenar energía elástica. Usualmente se considera que es un material elástico incompresible e isótropo. En los seres humanos, el gen que codifica la fabricación de la elastina es el gen ELN.
Abstract from DBpedia / Wikipedia · CC BY-SA