Structure via PubChem · Public domain (PubChem)
enocitabine
Sign in to saveEnocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.
Chemical data
- Formula
- C31H55N3O6
- Molecular weight
- 565.8 g/mol
- IUPAC name
- N-[1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]docosanamide
- SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
- InChIKey
- SAMRUMKYXPVKPA-VFKOLLTISA-N
- XLogP
- 9.2
- Polar surface area
- 132 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
179 papers- Phase 1 trial of gemtuzumab ozogamicin in combination with enocitabine and daunorubicin for elderly patients with relapsed or refractory acute myeloid leukemia: Japan Adult Leukemia Study Group (JALSG)-GML208 study.International journal of hematology · 2012
- [Cytarabine].Gan to kagaku ryoho. Cancer & chemotherapy · 1987
- [Cytidine].Nihon rinsho. Japanese journal of clinical medicine · 2015
- Clinical pharmacokinetics of cytarabine formulations.Clinical pharmacokinetics · 2002
- [Acute myeloid leukemia of the elderly: recent progresses in therapy].[Rinsho ketsueki] The Japanese journal of clinical hematology · 2018
via PubMed
Wikidata facts
- Mass
- 565.409
Show 4 more facts
- chemical formula
- C₃₁H₅₅N₃O₆
- Commons category
- Enocitabine
- isomeric SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
- canonical SMILES
- CCCCCCCCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Enocitabine (INN, marketed under the brand name Sunrabin) is a nucleoside analog used as chemotherapy.
Sunrabin contains the emulsifier HCO-60, which can cause allergic reactions.
Excerpted from Wikipedia’s “enocitabine” article, available under the CC BY-SA 4.0 licence.