ethyl eicosapentaenoate

Chemical data

Formula

C22H34O2

Molecular weight

330.5 g/mol

IUPAC name

ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate

SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)OCC

InChIKey

SSQPWTVBQMWLSZ-AAQCHOMXSA-N

XLogP

6.3

Polar surface area

26.3 Ų

H-bond donors

0

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

2012

Admin. routes

oral

Indications

cardiovascular disease, Hypertriglyceridemia, colorectal adenoma, non-alcoholic steatohepatitis

via ChEMBL · EBI

• Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.The New England journal of medicine · 2019
• Ethyl-eicosapentaenoate and dexamethasone resistance in therapy-refractory depression.The international journal of neuropsychopharmacology · 2004
• Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial.European heart journal · 2020
• 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in Adults.The Canadian journal of cardiology · 2021
• Icosapent ethyl reduces arterial thrombosis by inhibition of cyclooxygenase-1-induced platelet reactivity.Science translational medicine · 2025

via PubMed

Wikidata facts

Mass

330.256

Has use

medication

via Wikidata · CC0