EXOC1
Sign in to saveAlso known as BM-102, SEC3, SEC3L1, SEC3P, exocyst complex component 1
Exocyst complex component 1 is a protein that in humans is encoded by the EXOC1 gene.
Gene data
EXOC1- Name
- exocyst complex component 1
- Type
- protein-coding
- Position
- 55,853,628–55,905,165 (+)
- Aliases
- BM-102, SEC3, SEC3L1, SEC3P
- Ensembl
- ENSG00000090989
- RefSeq RNA
- NM_001024924.2, NM_018261.4, NM_178237.3, XM_005265747.4, XM_005265748.2
- RefSeq protein
- NP_001020095.1, NP_060731.2, NP_839955.1, XP_005265804.1, XP_005265805.1
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
exocyst complex component 1
- Symbol
- EXOC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:55,853,628-55,905,165
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 41241
- genetic association
- cervix uterine cancer
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55763
- genomic end
- 55905086
- genomic start
- 55853648
- chromosome
- human chromosome 4
- cytogenetic location
- 4q12
- expressed in
- germinal epithelium
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Exocyst complex component 1 is a protein that in humans is encoded by the EXOC1 gene.
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Excerpted from Wikipedia’s “EXOC1” article, available under the CC BY-SA 4.0 licence.