EXOSC10
Sign in to saveAlso known as PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3
protein-coding gene in the species Homo sapiens
Gene data
EXOSC10- Name
- exosome component 10
- Type
- protein-coding
- Position
- 11,066,613–11,099,907 (−)
- Aliases
- PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
- Ensembl
- ENSG00000171824
- RefSeq RNA
- NM_001001998.3, NM_002685.4, XM_005263475.3, XM_047422661.1, XM_047422663.1
- RefSeq protein
- NP_001001998.1, NP_002676.1, XP_005263532.2, XP_047278617.1, XP_047278619.1
Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex). [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
maturation of 5.8S rRNAexonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)nuclear-transcribed mRNA catabolic processrRNA processingRNA processingRNA processingRNA catabolic process
Molecular function
Pathways
via MyGene.info