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fagopyrin

Structure via PubChem · Public domain (PubChem)

EntityQ2608430· pop 8· linked from 3 articles

Fagopyrin is a phototoxic substance found in the flowers of buckwheat (Fagopyrum esculentum). Their chemical structure contains a naphthodianthrone skeleton similar to that of hypericin. After exposure, fagopyrin can cause sensitivity to light, also called fagopyrism, an itchy skin rash.

Chemical data

Formula
C40H34N2O8
Molecular weight
670.7 g/mol
IUPAC name
5,7,11,18,22,24-hexahydroxy-13,16-dimethyl-6,23-di(piperidin-2-yl)octacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(27),2(28),3,5,7,10,12,14,16,18,21,23,25-tridecaene-9,20-dione
SMILES
CC1=CC(=C2C3=C4C5=C6C(=C13)C(=CC(=C6C(=O)C7=C(C(=C(C(=C57)C8=C4C(=C(C(=C8O)C9CCCCN9)O)C2=O)O)C1CCCCN1)O)O)C)O
InChIKey
ROFJUMITFMRBRF-UHFFFAOYSA-N
XLogP
7.4
Polar surface area
180 Ų
H-bond donors
8
H-bond acceptors
10
Formal charge
0

via PubChem

Wikidata facts

Mass
670.231516
Show 3 more facts
chemical formula
C₄₀H₃₄N₂O₈
canonical SMILES
CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C(=C(C7=C6C5=C3C8=C7C(=C(C(=C8C2=O)O)C9CCCCN9)O)O)C1CCCCN1)O)O
Commons category
Fagopyrin
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

5 sections
Contents
  • History and occurrence
  • Structure
  • Biosynthesis and properties
  • References
  • External links

Fagopyrin is a phototoxic substance found in the flowers of buckwheat (Fagopyrum esculentum). Their chemical structure contains a naphthodianthrone skeleton similar to that of hypericin. After exposure, fagopyrin can cause sensitivity to light, also called fagopyrism, an itchy skin rash.

== History and occurrence == The substance was isolated from flowers of the red-flowering genotype of buckwheat in 1941, and its chemical structure, which is derived from hypericin, was first described in 1979. Within the edible parts of the plant, it is found exclusively in the brown fruit husk of buckwheat grains.

Excerpted from Wikipedia’s “fagopyrin” article, available under the CC BY-SA 4.0 licence.

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