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simplified molecular input line entry specification

File:SMILES.png · Wikimedia Commons · See Wikimedia Commons

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simplified molecular input line entry specification

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Also known as SMILES, .smi, simplified molecular-input line-entry system

ASCII line notation for the structure of chemical species

Key facts

Filename extension
.smi
Internet media type
chemical/x-daylight-smiles
Type of format
chemical file format

via Wikipedia infobox

~21 min read

Encyclopedic overview

SMILES generation algorithm for ciprofloxacin: break cycles, then write as branches off a main backbone

The Simplified Molecular Input Line Entry System (SMILES) is a specification in the form of a line notation for describing the structure of chemical species using short ASCII strings. SMILES strings can be imported by most molecule editors for conversion back into two-dimensional drawings or three-dimensional models of the molecules.

Excerpted from Wikipedia’s “simplified molecular input line entry specification” article, available under the CC BY-SA 4.0 licence.

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