FAM3C
Sign in to saveAlso known as ILEI, GS3786, family with sequence similarity 3 member C, FAM3 metabolism regulating signaling molecule C
Protein FAM3C is a protein that in humans is encoded by the FAM3C gene.
Gene data
FAM3C- Name
- FAM3 metabolism regulating signaling molecule C
- Type
- protein-coding
- Position
- 121,347,792–121,398,471 (−)
- Aliases
- GS3786, ILEI
- Ensembl
- ENSG00000196937
- RefSeq RNA
- NM_001040020.2, NM_014888.3, XM_011515736.3, XM_011515737.3, XM_047419771.1
- RefSeq protein
- NP_001035109.1, NP_055703.1, XP_011514038.1, XP_011514039.1, XP_047275727.1
This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. [provided by RefSeq, Mar 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
FAM3 metabolism regulating signaling molecule C
- Symbol
- FAM3C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:121,347,792-121,398,471
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8926
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10447
- genomic end
- 121036418
- genomic start
- 121348878
- chromosome
- human chromosome 7
- cytogenetic location
- 7q31.31
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Protein FAM3C is a protein that in humans is encoded by the FAM3C gene.
== Function == This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Alternate transcriptional splice variants which encode the same protein have been characterized. FAM3C functions and expression also were studied in mammalian brains which shown that a reduced FAM3C level associated to the onset of sporadic Alzheimer's disease (AD), which highlighted FAM3C as a promising therapeutic target for Alzheimer's disease. Moreover, level of FAM3C was claimed to be a biomarker for AD together with saposin D.
Excerpted from Wikipedia’s “FAM3C” article, available under the CC BY-SA 4.0 licence.