FBXL4

Name

F-box and leucine rich repeat protein 4

Type

protein-coding

Position

98,868,535–98,948,006 (−)

Aliases

FBL4, FBL5, MTDPS13

Ensembl

ENSG00000112234

RefSeq RNA

NM_001278716.2, NM_012160.5, NR_103836.2, NR_103837.2, XM_005266930.4

RefSeq protein

NP_001265645.1, NP_036292.2, XP_005266987.1, XP_016866215.1, XP_016866216.1

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

via MyGene.info

Gene · Ensembl

F-box and leucine rich repeat protein 4

Symbol

FBXL4

Biotype

Protein coding

Organism

Homo sapiens

Location

6:98,868,535-98,948,006

Strand

Reverse (−)

Assembly

GRCh38