FBXO2
Sign in to saveAlso known as FBG1, FBX2, Fbs1, NFB42, OCP1, F-box protein 2
F-box only protein 2 is a protein that in humans is encoded by the FBXO2 gene.
Gene data
FBXO2- Name
- F-box protein 2
- Type
- protein-coding
- Position
- 11,637,018–11,655,785 (−)
- Aliases
- FBG1, FBX2, Fbs1, NFB42, OCP1
- Ensembl
- ENSG00000116661
- RefSeq RNA
- NM_012168.6
- RefSeq protein
- NP_036300.2
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
F-box protein 2
- Symbol
- FBXO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:11,637,018-11,655,785
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
F-box only protein 2 is a protein that in humans is encoded by the FBXO2 gene.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
Excerpted from Wikipedia’s “FBXO2” article, available under the CC BY-SA 4.0 licence.