FBXO28
Sign in to saveAlso known as CENP-30, Fbx28, F-box protein 28, DEE100
F-box only protein 28 is a protein that in humans is encoded by the FBXO28 gene.
Gene data
FBXO28- Name
- F-box protein 28
- Type
- protein-coding
- Position
- 224,114,086–224,162,047 (+)
- Aliases
- CENP-30, DEE100, Fbx28
- Ensembl
- ENSG00000143756
- RefSeq RNA
- NM_001136115.3, NM_015176.4, NR_049764.2
- RefSeq protein
- NP_001129587.1, NP_055991.1
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
F-box protein 28
- Symbol
- FBXO28
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:224,114,086-224,162,047
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
F-box only protein 28 is a protein that in humans is encoded by the FBXO28 gene.
Members of the F-box protein family, such as FBXO28, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004).[supplied by OMIM]
Excerpted from Wikipedia’s “FBXO28” article, available under the CC BY-SA 4.0 licence.