FCER1A
Sign in to saveAlso known as FCE1A, FcERI, Fc fragment of IgE receptor Ia
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, also known as FCER1A, is a protein which in humans is encoded by the FCER1A gene.
Gene data
FCER1A- Name
- Fc epsilon receptor Ia
- Type
- protein-coding
- Position
- 159,289,714–159,308,224 (+)
- Aliases
- FCE1A, FCERIA, FcERI
- Ensembl
- ENSG00000179639
- RefSeq RNA
- NM_001387280.1, NM_001387281.1, NM_001387282.1, NM_002001.4
- RefSeq protein
- NP_001374209.1, NP_001374210.1, NP_001374211.1, NP_001992.1
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
Fc epsilon receptor Ia
- Symbol
- FCER1A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:159,289,714-159,308,224
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FCER1A PDB 1f2q.png
Show 8 more facts
- HomoloGene ID
- 1516
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2205
- genomic end
- 159278014
- genomic start
- 159259504
- chromosome
- human chromosome 1
- cytogenetic location
- 1q23.2
- expressed in
- gallbladder
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, also known as FCER1A, is a protein which in humans is encoded by the FCER1A gene.
== Function ==
Excerpted from Wikipedia’s “FCER1A” article, available under the CC BY-SA 4.0 licence.