FCHSD2
Sign in to saveAlso known as NWK, SH3MD3, FCH and double SH3 domains 2, NWK1
Genen från arten Homo sapiens
Gene data
FCHSD2- Name
- FCH and double SH3 domains 2
- Type
- protein-coding
- Position
- 72,836,042–73,142,485 (−)
- Aliases
- NWK, NWK1, SH3MD3
- Ensembl
- ENSG00000137478
- RefSeq RNA
- NM_014824.3, XM_011545409.2, XM_011545410.3, XM_047427949.1, XM_047427950.1
- RefSeq protein
- NP_055639.2, XP_011543711.1, XP_011543712.1, XP_047283905.1, XP_047283906.1
Enables phosphatidylinositol-3,4,5-trisphosphate binding activity and phosphatidylinositol-3,4-bisphosphate binding activity. Involved in clathrin-dependent endocytosis and positive regulation of Arp2/3 complex-mediated actin nucleation. Located in plasma membrane. Colocalizes with clathrin-coated pit. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
neuromuscular synaptic transmissionregulation of actin filament polymerizationpositive regulation of actin filament polymerizationpositive regulation of actin filament polymerizationpositive regulation of cytoskeleton organizationmembrane organizationmembrane organizationclathrin-dependent endocytosis
Molecular function
via MyGene.info
Gene · Ensembl
FCH and double SH3 domains 2
- Symbol
- FCHSD2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:72,836,042-73,142,485
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein FCHSD2 PDB 2dl5.png
Show 8 more facts
- HomoloGene ID
- 8887
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9873
- genomic end
- 73142318
- genomic start
- 72547790
- chromosome
- human chromosome 11
- cytogenetic location
- 11q13.4
- expressed in
- appendix
Sources (4)
via Wikidata · CC0