FCRL4
Sign in to saveAlso known as CD307d, FCRH4, IGFP2, IRTA1, Fc receptor like 4
Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.
Gene data
FCRL4- Name
- Fc receptor like 4
- Type
- protein-coding
- Position
- 157,573,747–157,598,085 (−)
- Aliases
- CD307d, FCRH4, IGFP2, IRTA1
- Ensembl
- ENSG00000163518
- RefSeq RNA
- NM_031282.3, XM_011510034.2, XM_054338965.1
- RefSeq protein
- NP_112572.1, XP_011508336.1, XP_054194940.1
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
Fc receptor like 4
- Symbol
- FCRL4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:157,573,747-157,598,085
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.
==References==
Excerpted from Wikipedia’s “FCRL4” article, available under the CC BY-SA 4.0 licence.