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febrifugine

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EntityQ5413935· pop 6· linked from 7 articles

febrifugine

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Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea. Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.

Chemical data

Formula
C16H19N3O3
Molecular weight
301.34 g/mol
IUPAC name
3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
301.143
Show 4 more facts
chemical formula
C₁₆H₁₉N₃O₃
canonical SMILES
C1CC(C(NC1)CC(=O)CN2C=NC3=CC=CC=C3C2=O)O
isomeric SMILES
C1C[C@H]([C@@H](NC1)CC(=O)CN2C=NC3=CC=CC=C3C2=O)O
found in taxon
Hydrangea macrophylla
Sources (1)

via Wikidata · CC0

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Encyclopedic overview

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Contents
  • References

{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 441877885 | ImageFile = Febrifugine.png | ImageSize = 200px | IUPACName = 3-{3-[(2R,3S)-3-Hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one | OtherNames = |Section1= |Section2= |Section3= }}

Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea. Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.

Excerpted from Wikipedia’s “febrifugine” article, available under the CC BY-SA 4.0 licence.

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