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ProteinQ9141217· pop 10· linked from 22 articles

Ferredoxin 1

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Also known as Ferredoxin-1, adrenodoxin, mitochondrial, mitochondrial adrenodoxin, FDX1, hepatoredoxin, adrenal ferredoxin

mammalian protein found in Homo sapiens

Protein · UniProt

Adrenodoxin, mitochondrial

Gene
FDX1
Organism
Homo sapiens (Human)
Length
184 aa
Molecular mass
19,393 Da
Evidence
1: Evidence at protein level

Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity)

2Fe-2S3D-structureAcetylationCholesterol metabolismElectron transportIronIron-sulfurLipid metabolism
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Swiss-Prot (reviewed) · via UniProt

Wikidata facts

Instance of
protein
Image
Protein FDX1 PDB 1ayf.png
Show 4 more facts
found in taxon
Homo sapiens
biological process
electron transport chain
cell component
mitochondrial matrix
Commons category
Adrenodoxin
Sources (4)

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