Ferredoxin 2
Sign in to saveAlso known as Ferredoxin-1-like protein, ferredoxin 1 like, FDX2, adrenodoxin-like protein, mitochondrial, FDX1L, ferredoxin-2, mitochondrial
Ferredoxin 2 is a protein that in humans is encoded by the FDX2 gene. It participates in heme A synthesis and iron-sulphur protein synthesis.
Protein · UniProt
Ferredoxin-2, mitochondrial
- Gene
- FDX2
- Organism
- Homo sapiens (Human)
- Length
- 183 aa
- Molecular mass
- 19,521 Da
- Evidence
- 1: Evidence at protein level
Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU (PubMed:28001042). The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis (By similarity). This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner (By similarity…
Swiss-Prot (reviewed) · via UniProt
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Article
2 sectionsContents
- References
- Further reading
Ferredoxin 2 is a protein that in humans is encoded by the FDX2 gene. It participates in heme A synthesis and iron-sulphur protein synthesis.
Mutations in FDX2 cause mitochondrial myopathy.