FHOD1
Sign in to saveAlso known as FHOS, formin homology 2 domain containing 1
FH1/FH2 domain-containing protein 1 is a protein that in humans is encoded by the FHOD1 gene.
Gene data
FHOD1- Name
- formin homology 2 domain containing 1
- Type
- protein-coding
- Position
- 67,229,387–67,247,539 (−)
- Aliases
- FHOS
- Ensembl
- ENSG00000135723
- RefSeq RNA
- NM_001318202.2, NM_013241.3, XM_011523043.3, XM_011523044.2, XM_047433999.1
- RefSeq protein
- NP_001305131.1, NP_037373.2, XP_011521345.1, XP_011521346.1, XP_047289955.1
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
formin homology 2 domain containing 1
- Symbol
- FHOD1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,229,387-67,247,539
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
FH1/FH2 domain-containing protein 1 is a protein that in humans is encoded by the FHOD1 gene.
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines.
Excerpted from Wikipedia’s “FHOD1” article, available under the CC BY-SA 4.0 licence.