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Key facts

Medical condition.name

Fibromyalgia

Medical condition.image

Widespread Pain Index Areas.svg

Medical condition.caption

Possible pain areas in the most used fibromyalgia diagnosis criteria (ACR 2016)

Medical condition.field

rheumatology, neurology

Medical condition.synonyms

Fibromyalgia syndrome

Medical condition.symptoms

Widespread pain, fatigue, sleep problems

Medical condition.onset

Early–middle age

Medical condition.duration

Long term

Medical condition.causes

Uncertain

Medical condition.diagnosis

Based on symptoms after ruling out other potential causes

Medical condition.differential

Anemia, autoimmune disorders (such as ankylosing spondylitis, polymyalgia rheumatica, rheumatoid arthritis, scleroderma, or multiple sclerosis), Lyme disease, osteoarthritis, thyroid disease

Medical condition.treatment

Sufficient sleep and exercise, medication

Medical condition.medication

Cyclobenzaprine, duloxetine, milnacipran, pregabalin

Medical condition.prognosis

Normal life expectancy

Medical condition.frequency

2%

via Wikipedia infobox

• Fibromyalgia: a clinical review.ReviewJAMA · 2014Clauw DJDOI: 10.1001/jama.2014.3266
• Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment.Nature reviews. Rheumatology · 2020Sarzi-Puttini P, Giorgi V, Marotto D et al.DOI: 10.1038/s41584-020-00506-w
• Fibromyalgia.ReviewAnnals of internal medicine · 2020Bair MJ, Krebs EEDOI: 10.7326/AITC202003030
• Fibromyalgia and Inflammation: Unrevealing the Connection.ReviewCells · 2025García-Domínguez MDOI: 10.3390/cells14040271
• Fibromyalgia Pathogenesis and Treatment Options Update.ReviewCurrent pain and headache reports · 2016Chinn S, Caldwell W, Gritsenko KDOI: 10.1007/s11916-016-0556-x
• Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers.ReviewMolecular pain · 2019D'Agnelli S, Arendt-Nielsen L, Gerra MC et al.DOI: 10.1177/1744806918819944
• Fibromyalgia.ReviewDisease-a-month : DM · 2015Jay GW, Barkin RLDOI: 10.1016/j.disamonth.2015.01.002
• Fibromyalgia.ReviewBMJ (Clinical research ed.) · 2014Rahman A, Underwood M, Carnes DDOI: 10.1136/bmj.g1224

via PubMed

Wikidata facts

Instance of

symptom or sign

Subclass of

disease

Image

Tender points fibromyalgia.svg

via Wikidata · CC0