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GeneQ18049338· pop 6· linked from 3 articles

Also known as C10orf4, F26C11.1-like, FRA10A, fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1, FRA10A associated CGG repeat 1

FRA10AC1 is a protein that in humans is encoded by the FRA10AC1 gene.

Gene data

FRA10AC1
Name
FRA10A associated CGG repeat 1
Type
protein-coding
Position
93,667,126–93,703,294 (−)
Aliases
C10orf4, F26C11.1-like, FRA10A, NEDGFC
RefSeq RNA
NM_001347712.2, NM_001347713.2, NM_001347714.2, NM_001347715.2, NM_145246.5
RefSeq protein
NP_001334641.1, NP_001334642.1, NP_001334643.1, NP_001334644.1, NP_660289.2

The protein encoded by this gene is a nuclear phosphoprotein of unknown function. This gene contains a tandem CGG repeat region within a CpG island that normally consists of 8-14 repeats but can expand to over 200 repeats. The repeat region is within the 5' UTR of some transcript variants, but is intronic to another variant. The expanded repeat allele is a fragile site and becomes hypermethylated, causing a reduction in gene expression. A disease phenotype has not been associated with expanded alleles. This gene is found within the rare FRA10A folate-sensitive fragile site. [provided by RefSeq, Dec 2016].

Gene Ontology

Molecular function

Cellular component

via MyGene.info

Gene · Ensembl

FRA10A associated CGG repeat 1

Symbol
FRA10AC1
Biotype
Protein coding
Organism
Homo sapiens
Location
10:93,667,126-93,703,294
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

3 sections
Contents
  • Function
  • References
  • Further reading

FRA10AC1 is a protein that in humans is encoded by the FRA10AC1 gene.

== Function ==

Excerpted from Wikipedia’s “FRA10AC1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0