Also known as ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, FUS RNA binding protein, altFUS
Gen der Spezies Homo sapiens
Gene data
FUS- Name
- FUS RNA binding protein
- Type
- protein-coding
- Position
- 31,180,131–31,196,963 (+)
- Aliases
- ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS, altFUS
- Ensembl
- ENSG00000089280
- RefSeq RNA
- NM_001010850.1, NM_001170634.1, NM_001170937.1, NM_004960.4, NR_028388.2
- RefSeq protein
- NP_001164105.1, NP_001164408.1, NP_004951.1, XP_011544083.1, XP_011544084.1
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
FUS RNA binding protein
- Symbol
- FUS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:31,180,131-31,196,963
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Fused in sarcoma.png
Show 6 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2521
- genomic start
- 31180138
- chromosome
- human chromosome 16
- genomic end
- 31191605
- cytogenetic location
- 16p11.2
via Wikidata · CC0