GAS2L1
Sign in to saveAlso known as GAR22, growth arrest specific 2 like 1
GAS2-like protein 1 is a protein that in humans is encoded by the GAS2L1 gene.
Gene data
GAS2L1- Name
- growth arrest specific 2 like 1
- Type
- protein-coding
- Position
- 29,306,394–29,312,787 (+)
- Aliases
- GAR22
- Ensembl
- ENSG00000185340
- RefSeq RNA
- NM_001278730.2, NM_001362985.3, NM_001395196.1, NM_001395197.1, NM_006478.5
- RefSeq protein
- NP_001265659.1, NP_001349914.1, NP_001382125.1, NP_001382126.1, NP_006469.2
This gene encodes a member of the growth arrest-specific 2 protein family. This protein binds components of the cytoskeleton and may be involved in mediating interactions between microtubules and microfilaments. This protein localizes to the proximal end of mature centrioles and links centrosomes to both microtubules and actin. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, May 2018].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
growth arrest specific 2 like 1
- Symbol
- GAS2L1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:29,306,394-29,312,787
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 4733
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10634
- genomic end
- 29708774
- genomic start
- 29702572
- chromosome
- human chromosome 22
- cytogenetic location
- 22q12.2
- expressed in
- parotid gland
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
GAS2-like protein 1 is a protein that in humans is encoded by the GAS2L1 gene.
The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene.
Excerpted from Wikipedia’s “GAS2L1” article, available under the CC BY-SA 4.0 licence.