GFI1B
Sign in to saveAlso known as BDPLT17, ZNF163B, growth factor independent 1B transcriptional repressor
Zinc finger protein Gfi-1b is a protein that in humans is encoded by the GFI1B gene.
Gene data
GFI1B- Name
- growth factor independent 1B transcriptional repressor
- Type
- protein-coding
- Aliases
- BDPLT17, ZNF163B
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014].
via MyGene.info
Gene · Ensembl
growth factor independent 1B transcriptional repressor
- Symbol
- GFI1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:132,944,000-132,991,687
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 31223
- exact match
- identifiers.org/ncbigene/8328
- genomic end
- 135867083
- genomic start
- 135820932
- cytogenetic location
- 9q34.13
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Zinc finger protein Gfi-1b is a protein that in humans is encoded by the GFI1B gene.
==References==