GGA3
Sign in to saveAlso known as golgi associated, gamma adaptin ear containing, ARF binding protein 3
ADP-ribosylation factor-binding protein GGA3 is a protein that in humans is encoded by the GGA3 gene.
Gene data
GGA3- Name
- golgi associated, gamma adaptin ear containing, ARF binding protein 3
- Type
- protein-coding
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010].
via MyGene.info
Wikidata facts
- Image
- Protein GGA3 PDB 1jpl.png
Show 6 more facts
- HomoloGene ID
- 121703
- exact match
- identifiers.org/ncbigene/23163
- genomic end
- 73258444
- genomic start
- 73232694
- cytogenetic location
- 17q25.1
- Commons category
- ADP-ribosylation factor-binding protein GGA3
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ADP-ribosylation factor-binding protein GGA3 is a protein that in humans is encoded by the GGA3 gene.
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Alternative splicing of this gene results in two transcript variants.