Skip to content
EntityQ770843· pop 16· linked from 146 articles

glucagonoma

Sign in to save

Glucagonoma is a very rare tumor of the alpha cells of the pancreas that results in the overproduction of the hormone glucagon. Typically associated with a rash called necrolytic migratory erythema, weight loss, and mild diabetes mellitus, most people with glucagonoma contract it spontaneously. However, about 10% of cases are associated with multiple endocrine neoplasia type 1 (MEN-1) syndrome.

In the Vinony graph

Within Vinony's link graph, glucagonoma is referenced by 146 other articles, and connects out to pancreatic cancer, alpha cell and Hurthle cell.

Vinony files it under Endocrine neoplasia and Rare cancers.

Its subject is documented across 16 Wikipedia language editions.

Key facts

Medical condition (new).name
Glucagonoma
Medical condition (new).caption
Skin changes associated with Glucagonoma
Medical condition (new).field
Oncology

via Wikipedia infobox

Research

1,280 papers

via PubMed

Wikidata facts

Show 2 more facts
Sources (3)

via Wikidata · CC0

~4 min read

Encyclopedic overview

7 sections
Contents
  • Causes
  • Mechanism
  • Diagnosis
  • Treatment
  • History
  • References
  • External links

Glucagonoma is a very rare tumor of the alpha cells of the pancreas that results in the overproduction of the hormone glucagon. Typically associated with a rash called necrolytic migratory erythema, weight loss, and mild diabetes mellitus, most people with glucagonoma contract it spontaneously. However, about 10% of cases are associated with multiple endocrine neoplasia type 1 (MEN-1) syndrome.

== Causes == Although the cause of glucagonoma is unknown, some genetic factors may lead to the condition. A family history of multiple endocrine neoplasia type 1 (MEN1) is a risk factor. Additionally, those with Mahvash disease have an increased risk for glucagonoma, as the glucagon receptor gene (GCGR) is mutated.

Excerpted from Wikipedia’s “glucagonoma” article, available under the CC BY-SA 4.0 licence.

Connections

Categories